If you use Gmail and a Mac, Mailplane is a must have application. It’s really the first program I’ve seen that really takes a web based application to the desktop.

At it’s core, it’s really just a webkit browser (or so I assume) that shows Gmail. But then there is so much more. It has all Gmail features built into the application itself. Not only does it have a toolbar with all the standard buttons like new message, reply, forward and delete, but it also ties into iPhoto, has drag and drop attachment abilities, keychain support and Growl notifications. The latest version even works with GTalk to take it out of Gmail and into it’s own little window.